| Date | Opponent | Location | Time/Result | Media Links |
|---|
| Friday, 4 November 2016 | Wilmington | BB&T Arena | W, 102-54 | |
| Friday, 11 November 2016 | Earlham | BB&T Arena | W, 96-56 | |
| Sunday, 13 November 2016 | Illinois | State Farm Center | L, 79-64 | |
| Friday, 18 November 2016 | Austin Peay | Millett Hall | L, 77-69 | |
| Saturday, 19 November 2016 | Delaware | Millett Hall | W, 74-53 | |
| Sunday, 20 November 2016 | Miami (Ohio) | Millett Hall | W, 79-70 | |
| Saturday, 26 November 2016 | North Carolina Central | BB&T Arena | L, 82-74 | |
| Wednesday, 30 November 2016 | Morehead St. | Johnson Arena | W, 84-79 | |
| Saturday, 3 December 2016 | Norfolk St. | Joseph Echols Hall | W, 72-61 | |
| Wednesday, 7 December 2016 | Eastern Illinois | BB&T Arena | W, 80-70 | |
| Saturday, 10 December 2016 | Southeast Missouri St. | Show Me Center | W, 80-66 | |
| Sunday, 18 December 2016 | Eastern Washington | BB&T Arena | W, 70-48 | |
| Wednesday, 21 December 2016 | Brescia | BB&T Arena | W, 97-73 | |
| Friday, 23 December 2016 | West Virginia | WVU Coliseum | L, 92-61 | |
| Thursday, 29 December 2016 | Detroit | Calihan Hall | W, 81-70 | |
| Saturday, 31 December 2016 | Oakland | Athletics Center O’rena | L, 76-65 | |
| Thursday, 5 January 2017 | Youngstown St. | BB&T Arena | W, 83-70 | |
| Saturday, 7 January 2017 | Cleveland St. | BB&T Arena | W, 83-75 | |
| Tuesday, 10 January 2017 | Green Bay | Resch Center | L, 80-71 | |
| Thursday, 12 January 2017 | Milwaukee | Klotsche Center | L, 68-58 | |
| Friday, 20 January 2017 | Oakland | BB&T Arena | L, 79-70 | |
| Sunday, 22 January 2017 | Detroit | BB&T Arena | W, 101-87 | |
| Friday, 27 January 2017 | Illinois-Chicago | UIC Pavilion | W, 79-62 | |
| Sunday, 29 January 2017 | Valparaiso | Athletics-Recreation Center | L, 65-58 | |
| Saturday, 4 February 2017 | Wright St. | Nutter Center | W, 83-79 | |
| Thursday, 9 February 2017 | Green Bay | BB&T Arena | W, 69-67 | |
| Saturday, 11 February 2017 | Milwaukee | BB&T Arena | W, 69-63 | |
| Thursday, 16 February 2017 | Cleveland St. | Wolstein Center | W, 62-60 | |
| Saturday, 18 February 2017 | Youngstown St. | Beeghly Center | L, 81-77 | |
| Tuesday, 21 February 2017 | Wright St. | BB&T Arena | W, 83-76 | |
| Friday, 24 February 2017 | Illinois-Chicago | BB&T Arena | W, 90-82 | |
| Sunday, 26 February 2017 | Valparaiso | BB&T Arena | W, 82-78 | |
| Sunday, 5 March 2017 | Wright St. | Joe Louis Arena | W, 82-77 | Horizon League Quarterfinals |
| Monday, 6 March 2017 | Youngstown St. | Joe Louis Arena | W, 84-74 | Horizon League Semifinals |
| Tuesday, 7 March 2017 | Milwaukee | Joe Louis Arena | W, 59-53 | Horizon League Finals |
| Friday, 17 March 2017 | Kentucky | Bankers Life Fieldhouse | 9:40 PM | NCAA Tournament First Round |